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1500 questions
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How do mRNA vaccines work and what are their advantages over traditional vaccines?
How do mRNA vaccines work?
To my intuitive understanding, for an mRNA vaccine to work, the mRNAs injected into the patient need to first enter a cell and get translated into proteins. Those proteins must then somehow exit the cell so that they can…

Remi.b
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How do pharmaceutical companies deal with people who received a placebo?
I would like to know what happens to the people in the vaccine studies who received a placebo.
Essentially they have not been vaccinated. However, in order for the study to stay blind so that long term effects can be observed, they cannot be told…

Burt
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Can I use a foot pedal to send mouse clicks and/or modifier keys ergonomically?
When using computers, I often want to send more inputs than my keyboard can. I once tried to use a foot pedal (a.k.a. footswitch) to send mouse clicks and modifier keys, but it seemed to put a lot of strain on my ankle. Is it possible to use a foot…

Franck Dernoncourt
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Is water an essential ingredient of alcohol based hand sanitizers?
The two WHO formulations (ethanol and IPA) make up the volume with distilled or boiled water. But is this water essential for the best efficacy of the cleanser or is it only to bulk it out?
In other words is dilute alcohol (75 - 80%) a better hand…

Peter Jennings
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Are betadine mouthwashes really effective against COVID-19?
Recently news have come up that betadine/povidone-iodine mouthwashes should be used for prevention of COVID-19.
Betadine is an antiseptic. We use it in our clinic to clean a wound or after minor surgeries eg. extraction.
So are betadine mouthwashes…

Ojasvi
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Are nitrites/nitrates in processed meat unhealthy?
A friend of mine has avoided eating any conventional processed meat products for almost a decade because he heard about a risk of cancer and/or prostate problems associated with consumption of nitrites and nitrates used as preservatives.
I have seen…

Nate Barbettini
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How can I clean an anesthesia machine after a Covid-19 patient?
Would I change sodalime after each patient or are the filters enough?

özlem Özkalaycı
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2 answers
Does bleach have to be diluted to be more effective to kill virus?
This page Bleach claims
Bleach is more effective at killing germs when diluted than when used
straight out of the bottle.
this other page (Spanish) Alcohol and Bleach are more effective against Coronavirus diluted claims the same
Disinfectants…

Pablo
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Can CPAP devices connected with oxygen sources be used as ventilators?
I want to inquire if CPAP devices can act as low performance ventilators, if they are connected to an oxygen source as well.
I am asking this question in regards to the covid-19 pandemic. There are only two websites which cover this in the entire…

ck1987pd
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Are there any central trackers for COVID-19 trials?
There are several aggregate central trackers for the spread of COVID-19. Like this one, for example.
Is there anything similar for trials? Or trials in the pipeline? Either vaccines or treatments?

Stevie Mahoney
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Why does COVID-19 appear more infectious than SARS?
The COVID-19 R0 factor is 2-3, while SARS had an R0 factor of 2-5. However, COVID-19 has infected around 130,000 people and growing, while SARS totalled just under 9000 people infected.
Why is COVID-19 spreading faster and wider than SARS? What…

WindDude
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What is the expected false positives/negatives for COVID-19 tests?
As of March 13, 45/301 people have tested positive/negative for COVID-19
in Florida. What is the expected false positives/negatives here?
UPDATE (March 14): 71/478 from what I consider the best source.

bobuhito
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Is there evidence that women feel cold faster than men?
There is a cliche saying that women freeze faster than men. Also, there have been several articles in health journals addressing this question. (e.g. this article: "Why women feel the cold more than men")
Is there any scientific evidence to support…

Kaadzia
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What protects Chinese provinces other than Hubei from COVID-19 outbreak?
In China, the largest number of reported COVID-19 infections was in Hubei province.
Other countries are experiencing exponential increase in reported infections, while the remainder of China is reporting relatively small numbers of…

Karsten Theis
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Why are people so worried about 2019-nCoV?
EDIT: After reading the comments and learning more about the current outbreak, I see that the premise of my question is incorrect. I mistakenly believed that the virus' mortality rate was around the same as that of the flu, when in fact it's much…

Ersin Akinci
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