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1500 questions
6
votes
1 answer
Maternal Mortality Ratio without healthcare
What is an estimation of Maternal Mortality Ratio (MMR, number of mother death per 100000 births) without professional healthcare? In other words, how often women die during childbirth in some wild tribes which do not use modern healthcare at all…
Andrej Adamenko
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6
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2 answers
What properties of a topical medication determine what percent is systemically absorbed (bioavailability)?
Some medications are applied topically for a local skin effect, such as:
Topical corticosteroids for eczema or psoriasis, of which approx 2% is absorbed systemically.
Topical tretinoin for acne, of which approximately 1 to 2% is absorbed…
Pherdindy
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6
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Does intermittent fasting induce autophagic cell death?
https://www.cancertherapyadvisor.com/home/tools/fact-sheets/intermittent-fasting-and-cancer/
In vitro and in vivo animal studies suggest that PF inactivates
pro-proliferative pathways, while enhancing differential stress
resistance in normal…
Sayaman
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6
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Why isn't paracetamol routinely combined with n-acetylcysteine?
Whether it's acute large dose paracetamol or long term regular dosage of paracetamol usage, it is a problem for the liver, ototoxic and even potentially life-threatening.
While one might question the use of paracetamol at all, for acute symptoms and…
LаngLаngС
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6
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Does light pollution affect sleep quality while already asleep?
Many articles on the internet write about melatonin and its effects, making you tired. A lot of articles also point out how the use of devices before going to bed in modern days likely decrease melatonin production. Therefore, making it harder to…
Bob Ortiz
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6
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1 answer
What is the "best" or most accurate way to measure bodily hydration?
We all know that there are important benefits to good hydration. No question there.
I recently heard about a study (unfortunately I didn't catch the author's name) concluding that water is not close to an optimal hydration solution. The report was…
anongoodnurse
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6
votes
2 answers
Are there beneficial compounds in cigarette smoke?
The UKPDS 50 study suggested that smokers experience lower rates of diabetic retinopathy
Somewhat counter-intuitively, smoking status was inversely related to the development of new lesions and to the progression of established retinopathy. This…
Jay K
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6
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1 answer
Barrett's esophagus (BO) and proton-pump inhibitors (PPIs)
I have come across an interview with a European gastroenterologist (apparently from 2006) where he argues that in cases where a reflux disease does not cause typical symptoms even the presence of a Barrett's esophagus (BO) does not indicate…
Drux
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6
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1 answer
If and why is McDonald's food considered extremely unhealthy?
From my childhood I remember vehement opposition to fast food in general and in particular to McDonald's. While I believe the notion that McDonald's is extremely unhealthy is obviously widespread, I will nonetheless provide an example to not seem…
gaazkam
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1 answer
Are all Type 2 diabetes effects caused by sugar levels?
I am trying to understand the various effects of Type 2, but I cannot seem to find a direct statement about this:
Are all the various symptoms/problems of Type 2 - neuropathy, heart health problems, etc. - caused specifically by the high blood sugar…
Maury Markowitz
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6
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2 answers
How much space should be in between taking an antidepressant and drinking coffee?
For stimulants such as Methylphenidate and coffee, it is at least an hour, so I read:
Stimulant + Stimulant = Stimulated. Don't take your Concerta with
coffee in future. Space them out at least an hour or so.
To be safe I do at least three…
BCLC
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6
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1 answer
How to explain the theory of the influence of purine and alcohol on the incidence of risk for gout in light of contradictory evidence?
A common thought is that dietary restrictions are recommended for people susceptible to gout.
These restrictions often focus on fructose, purines and alcohol: if a food or beverage is 'high' in these, they should be avoided, but that theory seems…
LаngLаngС
- 6,897
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6
votes
1 answer
What STDs can be transmitted if both parties have no open sores/cuts?
If I recall correctly, Chlamydia, HPV, Gonorrhea, syphilis, and HIV require both parties to have cuts/sores for transmission.
More specific questions, assuming no cuts/sores:
Possible transmitted diseases if saliva/semen/pre-cum/etc is…
Awesomenite
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1 answer
Is this a trick question about a fracture?
I'm a medical student. As an exercise, we got an x-ray photograph of the left hand of a patient who reports to have fallen onto this hand, and has pain at the location of the scaphoid bone.
The question we have to answer is whether there might be a…
Daniel S.
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6
votes
2 answers
No firm evidence for restoration of gut bacteria by probiotics?
I read two online articles on the use of probiotics to help maintain balance of gut bacteria when undergoing antibiotic treatment:
https://www.healthline.com/nutrition/what-to-eat-antibiotics
https://blog.bulletproof.com/restore-gut-flora
I was…
user2153235
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