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1500 questions
5
votes
1 answer
Countries where medical residents actually work normal hours
I recently finished my MD degree in Canada and am wondering what to do for a career. I know (after trying) I'm definitely not able to work the long hours residency programs in North America demand. I see that in some other countries the law…

Alexbib
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5
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1 answer
What happens when you swallow larger chunks of food?
We're advised to chew our food many times before swallowing which breaks the food down into small chunks before we swallow and send it off down to our stomachs. What happens if we were to swallow larger chunks of food?
Does it take longer to digest…

Aequitas
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Why is the period of gestation defined to be measured from 2 weeks before conception?
So the normal gestational period is defined to be "from the first day of the woman's last menstrual cycle to the current date.".
Why is that? Wouldn't the more natural definition be "from two weeks after the first day of the woman's last menstrual…

robert bristow-johnson
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What to do after being exposed to someone with the flu/cold
If I spent 45 minutes in a car with closed windows with someone that had a cold/flu, what would I have to do immediately after exiting the vehicle to reduce and if possible eliminate the chance of getting infected?

pnizzle
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Does microneedling treat hypertrophic acne scars?
It is well known that microneedling (MN) is an effective method in treating atrophic acne scars. But is it also useful in treating raised, hypertrophic acne scars? If so, how does it work (what is the mechanism behind)?
I ask because there are…

Lagrenge
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5
votes
1 answer
Question about "per person-years" stats in medical studies
I'm reading a study (Lou, et al. 2013) that says in the abstract
In the first 2 years, the rate of recurrence was higher among patients who had received neoadjuvant therapy (35 per 100 person-years) than those who had not (14 per 100…

justaskingaquestion
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Tuning fork examination - Bing's test
In Russian medical segment the concept of Bing's test is formulated in such manner ("Otolaryngology: A Manual in Two Volumes", ISBN: 978-5-388-00664-6): There are two pathways in conduction of Bing test - "classical" and "modern". In the "classical"…

Alexandr_Kabanets
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5
votes
1 answer
Do mRNA Vaccines tend to work only for a short period of time?
The two significant mRNA vaccines are for COVID and there effect is only about 6 months. Is there a cause and effect relationship here? That is, do mRNA vaccines tend to only last a short period of time?
Here is a site that says natural immunity…

Bob
- 171
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5
votes
1 answer
Maintain lactase while dairy free
My 2-month old daughter has a cow's milk intolerance, so my wife has stopped consuming dairy. Ideally she'll be breastfeeding until 12+ months, so if it persists it could be a year before she has dairy again.
We have a friend who was dairy free with…

Drew
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Does any mechanism of action exist that would allow topical application of jojoba oil to down-regulate sebum production?
This study found that adapalene (brand name Differin) suppresses "TG and PLIN1 production in differentiated hamster sebocytes" leading to the stated goal of "an inhibitory action for sebum accumulation." Thus, some mechanism of action exists to…

nat-72o
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5
votes
1 answer
Why do calcium channel blockers have an adverse effect of edema but Beta Blockers do not cause edema as a side effect?
My pharmacology professor glossed over the mechanism that causes edema besides briefly discussing after/preload. If Calcium channel blockers and beta blockers both are negative ionotropes then why isn't heart failure some form of adverse effect in…

Justin Edward
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5
votes
1 answer
Astigmatism eyeglass lenses -- how much distortion is normal?
I've been wearing glasses for near-sightedness for almost my entire life but only yesterday got glasses to correct my astigmatism. The world now looks rather distorted. To name two examples, my computer monitor appears to be a trapezoid (long side…

Mooseman
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2 answers
What makes Cialis cure Erectile Dysfunction permanently?
Referring to this published paper Efficacy and safety of once-daily tadalafil in men with erectile dysfunction who reported no successful intercourse attempts at baseline.
The posttreatment intercourse success rate was 32% and 46% for
tadalafil…

Graviton
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5
votes
3 answers
What is the meaning of "co-formulated"?
I was reading the The right drug for the right patient section of the University of Sydney website, which provides these clinical guidelines (flow chart), and says (bold my own):
There are no studies directly comparing these treatment
options and…

stevec
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votes
1 answer
How can I get a researcher to research a drug for my affliction?
I have a relatively rare disease, and just recently discovered that a drug helps me with some of my symptoms. The drug is not approved by the FDA for how I am using it.
Who do I contact, and how do I contact them, to get the research done so that…

Jack Swayze Sr
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