Small and simple Perl one-liner:
$ perl -ane 'printf "%s",@F[0];@F[0]="";print @F' <<< "2015-04-18 10:21:59 10 05430 -9999 -9999 000000000000"
2015-04-1810:21:591005430-9999-9999000000000000
Or even simpler as suggested by mik in comments:
perl -pe 's/ //' <<< "2015-04-18 10:21:59 10 05430 -9999 -9999 000000000000"
Python can do it too. Here's a small script that does the job. It can be reduced to a one-liner, if necessary:
#!/usr/bin/env python
from __future__ import print_function
import sys
for line in sys.stdin:
words=line.strip().split()
print(words[0],end="")
print(" ".join(words[1:]))
And with the same line in input file duplicated 3 times, here's a test for multi-line input:
$ ./remove_leading_space.py < input.txt
2015-04-1810:21:59 10 05430 -9999 -9999 000000000000
2015-04-1810:21:59 10 05430 -9999 -9999 000000000000
2015-04-1810:21:59 10 05430 -9999 -9999 000000000000
If you just one single line edited, you can do it like so:
$ ./remove_leading_space.py <<< "2015-04-18 10:21:59 10 05430 -9999 -9999 000000000000"