From a case report:
In addition, the authors started 5-hydroxytryptophan titrated to 400 mg orally twice daily with concomittant carbidopa 37.5 mg orally four times a day, and he responded with remission of suicidal ideation and significant improvement in depression and function.
Does "400 mg orally twice daily" translate into 800 mg of the drug per day, or does it mean "a total of 400 mg/day was divided into two daily doses"?