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Why *exactly* are mRNA covid vaccines delivered intramuscularly?
I would like to understand what exact processes make intramuscular injection of particularly mRNA covid vaccines the best delivery option. I've asked doctors and googled, but I get contradictory responses.
My understanding is that muscle cells are…
Jacek Kołodziejek
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5
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Best to replace amalgam filling with composite?
My question is whether it's best to replace amalgam fillings with newer, composite fillings. My concern is the constant, low-level of Hg leaching into the body. I understand that removing them will release more Hg into the body, but expect that, in…
Don Slowik
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Why aren't mRNA vaccines being updated for new variants?
From what I understand, updating an mRNA vaccine is trivial. According to this answer, no or small clinical trials would be needed to update the vaccine, and updating production would also be trivial. Why, then, are we still producing the original…
herman
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5
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1 answer
Bradyarrhythmia & Bradycardia- same or different?
Do Bradyarrhythmia & Bradycardia denote same abnormality or are there some finer differences between the two?? In text provided by my college, it appears bradycardia condition comes under the condition bradyarrhythmia..I tried searching about the…
Pearl Dua
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5
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1 answer
Does mouthwash provide any benefits?
I have came across two questions on the topic, however they both seem to assume that mouthwash is beneficial.
• How frequently should non-alcoholic mouthwashes be used?
• How often should I use mouthwash?
Is mouthwashing beneficial?
Gonçalo Peres
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5
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1 answer
Can foods one is not allergic to exacarbate atopic dermatitis?
Several physicians (incl. two profesors in allergology, regarded among highest authorities in allergology in my country) told me and insisted that people with atopic dermatitis must avoid certain foods for the rest of their lives, even if one is not…
gaazkam
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5
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Moderna vs Pfizer COVID-19 vaccine mechanisms
It is my understanding that both mRNA vaccines encode for a pathogen-like protein that prompts the immune system to bind to the simulated pathogen and render it harmless.
Does the Pfizer and Moderna encode for different proteins that are the same or…
gatorback
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Could the COVID-19 vaccine adversely impact healthy protein reception?
I'm not a health expert, just trying to understand possible long-term side effects of the vaccine, so if my terminology and thinking is off, feel free to correct.
The prominent vaccines right now are the mRNA vaccines that cause our cells to…
Ryan Saunders
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1 answer
(Why) doesn't Moderna's Covid vaccine have an INN?
Pfizer's and even more obscure mRNA vaccines that haven't been approved have an INN, which ends with -meran (e.g. CureVac's is "zorecimeran"). But as far as I can tell Moderna's vaccine doesn't have an INN. Why is that? Do they need to apply to the…
the gods from engineering
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Does the Sievert unit account for how concentrated the radiation dose was?
I often see different types of medical imaging effective doses compared to time required for an equivalent effective dose from background radiation.
For example, a dental x-ray is compared here:
... around 0.150 mSv for a full mouth series…
Curtis Howard
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1 answer
How old is the suppression/mitigation distinction in epidemiology?
The question is in the title, really. I have seen this distinction being made since March this year in regards to COVID-19 strategies, but how long have epidemiologists used this categorization? Is it in any classic textbooks? Has suppression been…
bgp2000
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5
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1 answer
Is there a simple plot comparing covid lethality to flu as a function of age?
There is so much arguing over covid-19 vs. influenza. I would like to have some solid data in my hands. Can anyone point to a simple graph of the following?
age vs. either CFR or IFR
with one line for covid-19 and another for flu.
For covid there is…
Alex
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5
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What is a semi-hollow organ?
This question was taken from an NREMT (EMT certification) test I took and will have to re-take, so the context is emergency medicine/first response. It asked me to list some semi-hollow organs. This was never covered in my class, it's not in my…
WhatAreSemiHollows
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1 answer
Could a living donor donate their liver multiple times in their lifetime?
While meditating about becoming a living organ donor, I was quite surprised to come across the following:
Within eight weeks, both the donor's and the recipient's livers will
be almost completely…
Ritesh Singh
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5
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1 answer
What does "parenchymal organs" mean?
I read across one sentence saying:
Iron overload is also common and equally detrimental, affecting parenchymal organs including the liver, heart and pancreas.
What is a parenchymal organ?
I know some online content says that parenchymal tissue is…
Code42
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