I have been using neovim for a long time and I have been using Ctrl + s to save and Ctrl + q to quit.
nmap <c-s> :w<CR>
imap <c-s> <Esc>:w<CR>a
nmap <c-q> :q<CR>
imap <c-q> <Esc>:q<CR>
Due to the unexpected behavior of nvim with coc I switched to vim. It's using the same configuration but Ctrl + s freezes the editor and Ctrl + q is required to unfreeze it. I'm using Simple Terminal and it does not freeze for Ctrl + s.
NVIM v0.4.2
VIM - Vi IMproved 8.1