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1500 questions
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Does "400 mg orally twice daily" mean "800 mg of drug per day"?
From a case report:
In addition, the authors started 5-hydroxytryptophan titrated to 400 mg orally twice daily with concomittant carbidopa 37.5 mg orally four times a day, and he responded with remission of suicidal ideation and significant…
CowperKettle
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Meaning of "at baseline" in "Detection of antibodies at baseline in schizophrenia or major depression"
From The basis for folinic acid treatment in neuro-psychiatric disorders by Ramaekers et al., 2016, at the very end of the article:
Because the presence of FRα antibodies can show significant serum titer fluctuations, we recommend collection of at…
CowperKettle
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What are the cause(s) of fibromyalgia?
Looking at The American College of Rheumatology 1990 criteria for the classification of fibromyalgia (Wolfe, et al. 1990), they indicate that this was first indentified in the late 1970s.
The seminal 1977 paper by Smythe and Moldofsky, “Two…
Unicorn Sue
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Type II Diabetes (T2D) Remission with Age?
Several medical providers have told an elderly relative that his T2D was probably not reversed through his (isocaloric) low-carb diet, rather that T2D generally goes away on its own in the elderly. That last phrase is the point of my question.
How…
lionel
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Is the number of push-ups a person can do a good risk estimate for heart attacks?
According to this article below, people who can do more than 40 push-ups have lower risk of heart attack. Is this a valid claim?
https://www.sciencealert.com/what-new-science-says-about-men-who-can-do-over-40-push-ups
EDIT:
Actual journal article:…
user781486
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How can a school be getting an epidemic of whooping cough if most of the students are vaccinated?
Apparently a private school is experiencing an outbreak of whooping cough. However, the article said that only 18 of the students in the school (out of 1500 or so) were unvaccinated, yet already 30 have the disease. Presumably some of the infected…
Tyler Durden
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Significantly reduced absorption of Ciprofloxacin with concurrently administered Sucralfate is utilized intentionally to treat Colitis?
Many studies proved that concurrent administration of Ciprofloxacin and Sucralfate reduces the maximum concentration of Ciprofloxacin in plasma to approximately 1/10 level.
Combined use of ciprofloxacin and…
Kay Lee
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Why isn't Biafine sold OTC in the US?
I wonder why the U.S. Food and Drug Administration approve Biafine for prescription only, i.e. cannot be sold OTC. Does Biafine contain any ingredients that are more harmful than other OTC drugs? It has been OTC in France for three decades.
Franck Dernoncourt
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Why aren't fluoride mouthwashes with cetylpyridinium chloride labeled as both anticavity and antibacterial?
I recall just a few years ago, there was a common misconception that fluoride interferes with the antibacterial activity of cetylpyridinium chloride (CPC) - in fact, I've often seen instructions on antibacterial CPC rinses specifying that you should…
user1258361
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Is BPA in can linings a health concern?
I've seen claims that canned food is bad for your health, because the linings often contain Bisphenol A (BPA). Is that true?
Please back up your answers with reliable references.
Cascabel
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2 answers
How much sleep do adults actually need?
The common consensus is that most adults should get 8 hours of sleep a night.
However, sleep needs are highly variable, with some people needing more to function properly, and some gaining little benefit past just a few hours. I'm trying to learn…
TheEnvironmentalist
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Rising allergy and intolerance diagnosis rates
A leading theory behind the rising allergy and intolerance diagnosis rates is the "hygiene hypothesis." This theory suggests that living conditions in much of the world might be too clean and that kids aren't being exposed to germs that train their…
Chris Rogers
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Is there any medical evidence that one toothbrush shape is better than another?
I've noticed that electric toothbrushes these days typically come in one of two shapes, or a combination of the two.
The first shape is a circular shape, where the bristles spin in a circle.
The second shape is the more traditional oblong shape…
End Anti-Semitic Hate
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Definition of Prevalence
I have been informed that the prevalence of chickenpox and smallpox in the general population are 10% and 0.1%, respectively. On the Wikipedia page it is written
Prevalence in epidemiology is the proportion of a particular population found to be…
John
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“There is a very strong correlation between consuming dairy products — such as milk — and acne, skin breakouts and aging.”
I read an article here that says:
“There is a very strong correlation between consuming dairy products —
such as milk — and acne, skin breakouts and aging.”
The reason? Hormones, Bella says. “Most of the cows used in farming
are actually…
user3486308
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